Notre Dame at USC (-6): The Trojans try to close out a CFP-caliber regular season with a tricky game against Notre Dame.
Neither team has played an elite opponent, so there's no telling what could happen. Michigan struggled for the first time against Illinois. Ohio State has won all of its games by double-digits, but that included a scoop-and-score with seconds remaining against Maryland to skew the numbers. Michigan at Ohio State (-8.5): The Game is truly the game of the year in college football as many expected, but Vegas oddsmakers are pessimistic about the competitiveness. Here are some of the most interesting opening lines for upcoming Week 13 matchups. There are five matchups on the docket between teams ranked last week in the College Football Playoff Rankings. The AAC and Sun Belt also have battles that could determine seeding and hosting championship games. Heading into Week 13, the matchup could be even bigger than anyone expected - but Vegas has a clear favorite.ĭown the board, USC, Oregon and LSU try to keep backdoor College Football Playoff hopes alive with competitive rivalry games. Everyone in college football has had The Game circled since Ohio State lost against Michigan last season to decide a College Football Playoff spot.
